The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome

Pathogenic Yersinia, including Y. pestis, the agent of plague in humans, and Y. pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host cells via a prototypical type III secretion system to promote pathogenesis. These effectors, termed Yersinia outer proteins (Yops),...

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Pubblicato in:Cell Host Microbe
Autori principali: Chung, Lawton K., Park, Yong Hwan, Zheng, Yueting, Brodsky, Igor E., Hearing, Patrick, Kastner, Daniel L., Chae, Jae Jin, Bliska, James B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025386/
https://ncbi.nlm.nih.gov/pubmed/27569559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.07.018
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