The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome

Pathogenic Yersinia, including Y. pestis, the agent of plague in humans, and Y. pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host cells via a prototypical type III secretion system to promote pathogenesis. These effectors, termed Yersinia outer proteins (Yops),...

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Publicat a:Cell Host Microbe
Autors principals: Chung, Lawton K., Park, Yong Hwan, Zheng, Yueting, Brodsky, Igor E., Hearing, Patrick, Kastner, Daniel L., Chae, Jae Jin, Bliska, James B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025386/
https://ncbi.nlm.nih.gov/pubmed/27569559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.07.018
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