The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses can also sense some T3SS components to initiate anti-bacterial mechanisms. Th...

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Vydáno v:PLoS Pathog
Hlavní autoři: Ratner, Dmitry, Orning, M. Pontus A., Proulx, Megan K., Wang, Donghai, Gavrilin, Mikhail A., Wewers, Mark D., Alnemri, Emad S., Johnson, Peter F., Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D., Lien, Egil
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135138/
https://ncbi.nlm.nih.gov/pubmed/27911947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006035
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