The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses can also sense some T3SS components to initiate anti-bacterial mechanisms. Th...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Ratner, Dmitry, Orning, M. Pontus A., Proulx, Megan K., Wang, Donghai, Gavrilin, Mikhail A., Wewers, Mark D., Alnemri, Emad S., Johnson, Peter F., Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D., Lien, Egil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135138/
https://ncbi.nlm.nih.gov/pubmed/27911947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006035
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