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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses can also sense some T3SS components to initiate anti-bacterial mechanisms. Th...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Ratner, Dmitry, Orning, M. Pontus A., Proulx, Megan K., Wang, Donghai, Gavrilin, Mikhail A., Wewers, Mark D., Alnemri, Emad S., Johnson, Peter F., Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D., Lien, Egil
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135138/
https://ncbi.nlm.nih.gov/pubmed/27911947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006035
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