The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses can also sense some T3SS components to initiate anti-bacterial mechanisms. Th...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Ratner, Dmitry, Orning, M. Pontus A., Proulx, Megan K., Wang, Donghai, Gavrilin, Mikhail A., Wewers, Mark D., Alnemri, Emad S., Johnson, Peter F., Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D., Lien, Egil
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135138/
https://ncbi.nlm.nih.gov/pubmed/27911947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006035
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