Bladder decompensation and reduction in nerve density in a rat model of chronic bladder outlet obstruction are attenuated with the NLRP3 inhibitor glyburide

Bladder outlet obstruction (BOO) leads to progressive voiding dysfunction. Acutely, obstruction triggers inflammation that drives bladder dysfunction. Over time, inflammation leads to decreased bladder nerve density and increased fibrosis, responsible for eventual decompensation and irreversibility....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Renal Physiol
Egile Nagusiak: Hughes, Francis M., Sexton, Stephanie J., Ledig, Patrick D., Yun, Chloe E., Jin, Huixia, Purves, J. Todd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383202/
https://ncbi.nlm.nih.gov/pubmed/30353742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00400.2018
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