The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction

PURPOSE: While bladder outlet obstruction (BOO) is well-established to elicit an inflammatory reaction in the bladder that leads to overactive bladder and fibrosis, little is known about the mechanism by which this is initiated. Nod-Like Receptors (NLRs) and the structures they form (inflammasomes)...

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Vydáno v:J Urol
Hlavní autoři: Hughes, Francis M., Hill, Hayden M., Wood, Case M., Edmondson, Andrew T., Dumas, Aliya, Foo, Wen-Chi, Oelsen, James M., Rac, Goran, Purves, J. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870136/
https://ncbi.nlm.nih.gov/pubmed/26707508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2015.12.068
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