Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β

Bladder outlet obstruction (BOO) triggers inflammation in the bladder through the NLRP3 inflammasome. BOO also activates fibrosis, which is largely responsible for the decompensation of the bladder in the chronic state. Because fibrosis can be driven by inflammation, we have explored a role for NLRP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Renal Physiol
Prif Awduron: Hughes, Francis M., Sexton, Stephanie J., Jin, Huixia, Govada, Vihasa, Purves, J. Todd
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625100/
https://ncbi.nlm.nih.gov/pubmed/28592436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00128.2017
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