AB279. SPR-06 Fibrosis in the bladder in response to outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β

OBJECTIVE: Bladder outlet obstruction (BOO), most commonly created by benign prostatic hyperplasia, promotes an inflammatory state that produces voiding dysfunction. Recently, we have shown that the NLRP3 inflammasome triggers this inflammation. Over time, inflammation promotes fibrosis. In this stu...

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Detalhes bibliográficos
Publicado no:Transl Androl Urol
Main Authors: Hughes, Francis M., Govada, Vihasa, Sexton, Stephanie, Purves, J. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Abstract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143233/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s279
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