AB279. SPR-06 Fibrosis in the bladder in response to outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β

OBJECTIVE: Bladder outlet obstruction (BOO), most commonly created by benign prostatic hyperplasia, promotes an inflammatory state that produces voiding dysfunction. Recently, we have shown that the NLRP3 inflammasome triggers this inflammation. Over time, inflammation promotes fibrosis. In this stu...

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Publié dans:Transl Androl Urol
Auteurs principaux: Hughes, Francis M., Govada, Vihasa, Sexton, Stephanie, Purves, J. Todd
Format: Artigo
Langue:Inglês
Publié: AME Publishing Company 2016
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Abstract
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143233/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s279
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