Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β

Bladder outlet obstruction (BOO) triggers inflammation in the bladder through the NLRP3 inflammasome. BOO also activates fibrosis, which is largely responsible for the decompensation of the bladder in the chronic state. Because fibrosis can be driven by inflammation, we have explored a role for NLRP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Physiol Renal Physiol
Päätekijät: Hughes, Francis M., Sexton, Stephanie J., Jin, Huixia, Govada, Vihasa, Purves, J. Todd
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625100/
https://ncbi.nlm.nih.gov/pubmed/28592436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00128.2017
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