NLRP3 / IL-1β mediates Denervation During Bladder Outlet Obstruction in Rats

AIMS: Denervation of the bladder is a detrimental consequence of bladder outlet obstruction (BOO). We have previously shown that, during BOO, inflammation triggered by the NLRP3 inflammasome in the urothelia mediates physiological bladder dysfunction and downstream fibrosis in rats. The aim of this...

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Detalhes bibliográficos
Publicado no:Neurourol Urodyn
Main Authors: Lütolf, Robin, Hughes, Francis M., Inouye, Brian M., Jin, Huixia, McMains, Jennifer C., Pak, Elena S., Hannan, Johanna L., Purves, J. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889355/
https://ncbi.nlm.nih.gov/pubmed/28984997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nau.23419
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