NLRP3 / IL-1β mediates Denervation During Bladder Outlet Obstruction in Rats

AIMS: Denervation of the bladder is a detrimental consequence of bladder outlet obstruction (BOO). We have previously shown that, during BOO, inflammation triggered by the NLRP3 inflammasome in the urothelia mediates physiological bladder dysfunction and downstream fibrosis in rats. The aim of this...

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Vydáno v:Neurourol Urodyn
Hlavní autoři: Lütolf, Robin, Hughes, Francis M., Inouye, Brian M., Jin, Huixia, McMains, Jennifer C., Pak, Elena S., Hannan, Johanna L., Purves, J. Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889355/
https://ncbi.nlm.nih.gov/pubmed/28984997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nau.23419
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