In vitro and in silico assessment of the developability of a designed monoclonal antibody library

Despite major advances in antibody discovery technologies, the successful development of monoclonal antibodies (mAbs) into effective therapeutic and diagnostic agents can often be impeded by developability liabilities, such as poor expression, low solubility, high viscosity and aggregation. Therefor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Wolf Pérez, Adriana-Michelle, Sormanni, Pietro, Andersen, Jonathan Sonne, Sakhnini, Laila Ismail, Rodriguez-Leon, Ileana, Bjelke, Jais Rose, Gajhede, Annette Juhl, De Maria, Leonardo, Otzen, Daniel E., Vendruscolo, Michele, Lorenzen, Nikolai
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6380425/
https://ncbi.nlm.nih.gov/pubmed/30523762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1556082
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados