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Protein Solubility Predictions Using the CamSol Method in the Study of Protein Homeostasis

One of the major functions of the protein homeostasis system is to maintain proteins in their soluble states, and indeed several human disorders are associated with the aberrant aggregation of proteins. An active involvement of the protein homeostasis system is necessary to avoid aggregation because...

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Опубликовано в: :Cold Spring Harb Perspect Biol
Главные авторы: Sormanni, Pietro, Vendruscolo, Michele
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886446/
https://ncbi.nlm.nih.gov/pubmed/30833455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a033845
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