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Rapid and accurate in silico solubility screening of a monoclonal antibody library

Antibodies represent essential tools in research and diagnostics and are rapidly growing in importance as therapeutics. Commonly used methods to obtain novel antibodies typically yield several candidates capable of engaging a given target. The development steps that follow, however, are usually perf...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sormanni, Pietro, Amery, Leanne, Ekizoglou, Sofia, Vendruscolo, Michele, Popovic, Bojana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558012/
https://ncbi.nlm.nih.gov/pubmed/28811609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07800-w
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