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Rapid and accurate in silico solubility screening of a monoclonal antibody library

Antibodies represent essential tools in research and diagnostics and are rapidly growing in importance as therapeutics. Commonly used methods to obtain novel antibodies typically yield several candidates capable of engaging a given target. The development steps that follow, however, are usually perf...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Sormanni, Pietro, Amery, Leanne, Ekizoglou, Sofia, Vendruscolo, Michele, Popovic, Bojana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558012/
https://ncbi.nlm.nih.gov/pubmed/28811609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07800-w
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