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Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins

Antibodies are powerful tools in life sciences research, as well as in diagnostic and therapeutic applications, because of their ability to bind given molecules with high affinity and specificity. Using current methods, however, it is laborious and sometimes difficult to generate antibodies to targe...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sormanni, Pietro, Aprile, Francesco A., Vendruscolo, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538631/
https://ncbi.nlm.nih.gov/pubmed/26216991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422401112
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