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Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
Antibodies are powerful tools in life sciences research, as well as in diagnostic and therapeutic applications, because of their ability to bind given molecules with high affinity and specificity. Using current methods, however, it is laborious and sometimes difficult to generate antibodies to targe...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538631/ https://ncbi.nlm.nih.gov/pubmed/26216991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422401112 |
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