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Rapid and accurate in silico solubility screening of a monoclonal antibody library

Antibodies represent essential tools in research and diagnostics and are rapidly growing in importance as therapeutics. Commonly used methods to obtain novel antibodies typically yield several candidates capable of engaging a given target. The development steps that follow, however, are usually perf...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Sormanni, Pietro, Amery, Leanne, Ekizoglou, Sofia, Vendruscolo, Michele, Popovic, Bojana
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558012/
https://ncbi.nlm.nih.gov/pubmed/28811609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07800-w
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