Wird geladen...
Occlusion of anion-binding exosite 2 in meizothrombin explains its impaired ability to activate factor V
The proteolytic conversion of factor V to factor Va is central for amplified flux through the blood coagulation cascade. Heterodimeric factor Va is produced by cleavage at three sites in the middle of factor V by thrombin, yielding an N terminus–derived heavy chain and a C terminus–derived light cha...
Gespeichert in:
| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6378960/ https://ncbi.nlm.nih.gov/pubmed/30578302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006510 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|