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Meizothrombin Is an Unexpectedly Zymogen-like Variant of Thrombin
Thrombin is produced by the ordered action of prothrombinase on two cleavage sites in prothrombin. Meizothrombin, a proteinase precursor of thrombin, is a singly cleaved species that accumulates abundantly as an intermediate. We now show that covalent linkage of the N-terminal propiece with the prot...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436291/ https://ncbi.nlm.nih.gov/pubmed/22815477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.394809 |
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