Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

OBJECTIVE: Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown. The objective of this study was to describe pharmacokinetics of morphine and...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Favié, Laurent M. A., Groenendaal, Floris, van den Broek, Marcel P. H., Rademaker, Carin M. A., de Haan, Timo R., van Straaten, Henrica L. M., Dijk, Peter H., van Heijst, Arno, Dudink, Jeroen, Dijkman, Koen P., Rijken, Monique, Zonnenberg, Inge A., Cools, Filip, Zecic, Alexandra, van der Lee, Johanna H., Nuytemans, Debbie H. G. M., van Bel, Frank, Egberts, Toine C. G., Huitema, Alwin D. R.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375702/
https://ncbi.nlm.nih.gov/pubmed/30763356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211910
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