Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

OBJECTIVE: Morphine is a commonly used drug in encephalopathic neonates treated with therapeutic hypothermia after perinatal asphyxia. Pharmacokinetics and optimal dosing of morphine in this population are largely unknown. The objective of this study was to describe pharmacokinetics of morphine and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Favié, Laurent M. A., Groenendaal, Floris, van den Broek, Marcel P. H., Rademaker, Carin M. A., de Haan, Timo R., van Straaten, Henrica L. M., Dijk, Peter H., van Heijst, Arno, Dudink, Jeroen, Dijkman, Koen P., Rijken, Monique, Zonnenberg, Inge A., Cools, Filip, Zecic, Alexandra, van der Lee, Johanna H., Nuytemans, Debbie H. G. M., van Bel, Frank, Egberts, Toine C. G., Huitema, Alwin D. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375702/
https://ncbi.nlm.nih.gov/pubmed/30763356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211910
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