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Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

Many neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis are characterized by the progressive appearance of abnormal proteinaceous assemblies in the nervous system. Studies in experimental systems indicate that the assemblies originate from...

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Bibliographic Details
Published in:Nat Neurosci
Main Authors: Jucker, Mathias, Walker, Lary C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375686/
https://ncbi.nlm.nih.gov/pubmed/30258241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0238-6
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