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Neurodegenerative Diseases: Expanding the Prion Concept
The prion paradigm has emerged as a unifying molecular principle for the pathogenesis of many age-related neurodegenerative diseases. This paradigm holds that a fundamental cause of specific disorders is the misfolding and seeded aggregation of certain proteins. The concept arose from the discovery...
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| Publicado no: | Annu Rev Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803040/ https://ncbi.nlm.nih.gov/pubmed/25840008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-071714-033828 |
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