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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

For several decades scientists have speculated that the key to understanding age-related neurodegenerative disorders may be found in the unusual biology of the prion diseases. Recently, owing largely to the advent of new disease models, this hypothesis has gained experimental momentum. In a remarkab...

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Detalhes bibliográficos
Main Authors: Jucker, Mathias, Walker, Lary C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963807/
https://ncbi.nlm.nih.gov/pubmed/24005412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12481
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