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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

For several decades scientists have speculated that the key to understanding age-related neurodegenerative disorders may be found in the unusual biology of the prion diseases. Recently, owing largely to the advent of new disease models, this hypothesis has gained experimental momentum. In a remarkab...

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Bibliographic Details
Main Authors: Jucker, Mathias, Walker, Lary C.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963807/
https://ncbi.nlm.nih.gov/pubmed/24005412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12481
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