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Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

For several decades scientists have speculated that the key to understanding age-related neurodegenerative disorders may be found in the unusual biology of the prion diseases. Recently, owing largely to the advent of new disease models, this hypothesis has gained experimental momentum. In a remarkab...

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Hlavní autoři: Jucker, Mathias, Walker, Lary C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963807/
https://ncbi.nlm.nih.gov/pubmed/24005412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12481
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