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Pathogenic Protein Seeding in Alzheimer’s Disease and Other Neurodegenerative Disorders
The misfolding and aggregation of specific proteins is a seminal occurrence in a remarkable variety of neurodegenerative disorders. In Alzheimer’s disease (the most prevalent cerebral proteopathy), the two principal aggregating proteins are β-amyloid (Aβ) and tau. The abnormal assemblies formed by c...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203752/ https://ncbi.nlm.nih.gov/pubmed/22028219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.22615 |
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