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Mechanisms of Protein Seeding in Neurodegenerative Diseases

Most age-associated neurodegenerative diseases involve the aggregation of specific proteins within the nervous system. In Alzheimer’s disease, the insidious pathogenic process begins many years before the symptoms emerge, and the lesions that characterize the disease – senile plaques and neurofibril...

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Detalhes bibliográficos
Main Authors: Walker, Lary C., Diamond, Marc I., Duff, Karen E., Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665718/
https://ncbi.nlm.nih.gov/pubmed/23599928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.1453
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