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Computational modelling of pathogenic protein spread in neurodegenerative diseases

Pathogenic protein accumulation and spread are fundamental principles of neurodegenerative diseases and ultimately account for the atrophy patterns that distinguish these diseases clinically. However, the biological mechanisms that link pathogenic proteins to specific neural network damage patterns...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Georgiadis, Konstantinos, Wray, Selina, Ourselin, Sébastien, Warren, Jason D., Modat, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798854/
https://ncbi.nlm.nih.gov/pubmed/29401516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192518
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