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Computational modelling of pathogenic protein spread in neurodegenerative diseases

Pathogenic protein accumulation and spread are fundamental principles of neurodegenerative diseases and ultimately account for the atrophy patterns that distinguish these diseases clinically. However, the biological mechanisms that link pathogenic proteins to specific neural network damage patterns...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Georgiadis, Konstantinos, Wray, Selina, Ourselin, Sébastien, Warren, Jason D., Modat, Marc
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798854/
https://ncbi.nlm.nih.gov/pubmed/29401516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192518
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