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Intercellular Spread of Protein Aggregates in Neurodegenerative Disease

Most neurodegenerative diseases are characterized by the accumulation of protein aggregates, some of which are toxic to cells. Mounting evidence demonstrates that in several diseases, protein aggregates can pass from neuron to neuron along connected networks, although the role of this spreading phen...

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Detalhes bibliográficos
Publicado no:Annu Rev Cell Dev Biol
Main Authors: Davis, Albert A., Leyns, Cheryl E.G., Holtzman, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350082/
https://ncbi.nlm.nih.gov/pubmed/30044648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cellbio-100617-062636
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