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Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease

Protein aggregates play a key role in the initiation and spreading of neurodegenerative disease but have been difficult to study due to their low abundance and heterogeneity, in both size and structure. Fluorescence based methods capable of detecting and characterising single aggregates have recentl...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta Proteins Proteom
Glavni autori: De, Suman, Klenerman, David
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676340/
https://ncbi.nlm.nih.gov/pubmed/30611780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2018.12.010
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