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Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease
Protein aggregates play a key role in the initiation and spreading of neurodegenerative disease but have been difficult to study due to their low abundance and heterogeneity, in both size and structure. Fluorescence based methods capable of detecting and characterising single aggregates have recentl...
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| Udgivet i: | Biochim Biophys Acta Proteins Proteom |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676340/ https://ncbi.nlm.nih.gov/pubmed/30611780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2018.12.010 |
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