Cargando...

G protein signaling–biased agonism at the κ-opioid receptor is maintained in striatal neurons

Biased agonists of G protein–coupled receptors may present a means to refine receptor signaling in a way that separates side effects from therapeutic properties. Several studies have shown that agonists that activate the κ-opioid receptor (KOR) in a manner that favors G protein coupling over β-arres...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Sci Signal
Autores principales: Ho, Jo-Hao, Stahl, Edward L., Schmid, Cullen L., Scarry, Sarah M., Aubé, Jeffrey, Bohn, Laura M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6373773/
https://ncbi.nlm.nih.gov/pubmed/30087177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aar4309
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!