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T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability
T cell receptor cross-reactivity allows a fixed T cell repertoire to respond to a much larger universe of potential antigens. Recent work has emphasized the importance of peptide structural and chemical homology, as opposed to sequence similarity, in T cell receptor cross-reactivity. Surprisingly th...
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| Опубликовано в: : | Nat Chem Biol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6371774/ https://ncbi.nlm.nih.gov/pubmed/30224695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0130-4 |
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