Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide-MHC complexes

Measurements of thermal stability by circular dichroism (CD) spectroscopy have been widely used to assess the binding of peptides to MHC proteins, particularly within the structural immunology community. Although thermal stability assays offer advantages over other approaches such as IC(50) measurem...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Hellman, Lance M., Yin, Liusong, Wang, Yuan, Blevins, Sydney J., Riley, Timothy P., Belden, Orrin S., Spear, Timothy T., Nishimura, Michael I., Stern, Lawrence J., Baker, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837003/
https://ncbi.nlm.nih.gov/pubmed/26906089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2016.02.016
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