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T cell receptor cross-reactivity expanded by dramatic peptide/MHC adaptability

T cell receptor cross-reactivity allows a fixed T cell repertoire to respond to a much larger universe of potential antigens. Recent work has emphasized the importance of peptide structural and chemical homology, as opposed to sequence similarity, in T cell receptor cross-reactivity. Surprisingly th...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael. I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371774/
https://ncbi.nlm.nih.gov/pubmed/30224695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0130-4
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