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Early stages of aggregation of engineered α-synuclein monomers and oligomers in solution
α-Synuclein is a protein that aggregates as amyloid fibrils in the brains of patients with Parkinson’s disease and dementia with Lewy bodies. Small oligomers of α-synuclein are neurotoxic and are thought to be closely associated with disease. Whereas α-synuclein fibrillization and fibril morphologie...
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| I publikationen: | Sci Rep |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group UK
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370846/ https://ncbi.nlm.nih.gov/pubmed/30741954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37584-6 |
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