Characterization of Heparin-induced Glyceraldehyde-3-phosphate Dehydrogenase Early Amyloid-like Oligomers and Their Implication in α-Synuclein Aggregation

Lewy bodies and Lewy neurites, neuropathological hallmarks of several neurological diseases, are mainly made of filamentous assemblies of α-synuclein. However, other macromolecules including Tau, ubiquitin, glyceraldehyde-3-phosphate dehydrogenase, and glycosaminoglycans are routinely found associat...

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Detalhes bibliográficos
Main Authors: Torres-Bugeau, Clarisa M., Ávila, César L., Raisman-Vozari, Rita, Papy-Garcia, Dulce, Itri, Rosangela, Barbosa, Leandro R. S., Cortez, Leonardo M., Sim, Valerie L., Chehín, Rosana N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268401/
https://ncbi.nlm.nih.gov/pubmed/22134915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303503
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