New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease

The causes of Parkinson disease (PD) remain mysterious, although some evidence supports mitochondrial dysfunctions and α-synuclein accumulation in Lewy bodies as major events. The abnormal accumulation of α-synuclein has been associated with a deficiency in the ubiquitin-proteasome system and the au...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Lehri-Boufala, Sonia, Ouidja, Mohand-Ouidir, Barbier-Chassefière, Véronique, Hénault, Emilie, Raisman-Vozari, Rita, Garrigue-Antar, Laure, Papy-Garcia, Dulce, Morin, Christophe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305359/
https://ncbi.nlm.nih.gov/pubmed/25617759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116641
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