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Cooperative inhibition of SNARE-mediated vesicle fusion by α-synuclein monomers and oligomers
The primary hallmark of Parkinson's disease (PD) is the generation of Lewy bodies of which major component is α-synuclein (α-Syn). Because of increasing evidence of the fundamental roles of α-Syn oligomers in disease progression, α-Syn oligomers have become potential targets for therapeutic int...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155056/ https://ncbi.nlm.nih.gov/pubmed/34040104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90503-0 |
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