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β-Amyloid and α-Synuclein Cooperate To Block SNARE-Dependent Vesicle Fusion

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are caused by β-amyloid (Aβ) and α-synuclein (αS), respectively. Ample evidence suggests that these two pathogenic proteins are closely linked and have a synergistic effect on eliciting neurodegenerative disorders. However, the pathophysiological...

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Vydáno v:Biochemistry
Hlavní autoři: Choi, Bong-Kyu, Kim, Jae-Yeol, Cha, Moon-Yong, Mook-Jung, Inhee, Shin, Yeon-Kyun, Lee, Nam Ki
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414064/
https://ncbi.nlm.nih.gov/pubmed/25714795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00087
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