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β-Amyloid and α-Synuclein Cooperate To Block SNARE-Dependent Vesicle Fusion

Alzheimer’s disease (AD) and Parkinson’s disease (PD) are caused by β-amyloid (Aβ) and α-synuclein (αS), respectively. Ample evidence suggests that these two pathogenic proteins are closely linked and have a synergistic effect on eliciting neurodegenerative disorders. However, the pathophysiological...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Choi, Bong-Kyu, Kim, Jae-Yeol, Cha, Moon-Yong, Mook-Jung, Inhee, Shin, Yeon-Kyun, Lee, Nam Ki
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414064/
https://ncbi.nlm.nih.gov/pubmed/25714795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00087
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