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Solution single-vesicle assay reveals PIP(2)-mediated sequential actions of synaptotagmin-1 on SNAREs
Synaptotagmin-1 (Syt1) is a major Ca(2+) sensor for synchronous neurotransmitter release, which requires vesicle fusion mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors). Syt1 utilizes its diverse interactions with target membrane (t-) SNARE, SNAREpin, and p...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3343461/ https://ncbi.nlm.nih.gov/pubmed/22407297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.57 |
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