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Synaptotagmin-1 Is an Antagonist for Munc18-1 in SNARE Zippering
In neuroexocytosis, SNAREs and Munc18-1 may consist of the minimal membrane fusion machinery. Consistent with this notion, we observed, using single molecule fluorescence assays, that Munc18-1 stimulates SNARE zippering and SNARE-dependent lipid mixing in the absence of a major Ca(2+) sensor synapto...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400360/ https://ncbi.nlm.nih.gov/pubmed/25716321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631341 |
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