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Synaptotagmin-1 Is an Antagonist for Munc18-1 in SNARE Zippering

In neuroexocytosis, SNAREs and Munc18-1 may consist of the minimal membrane fusion machinery. Consistent with this notion, we observed, using single molecule fluorescence assays, that Munc18-1 stimulates SNARE zippering and SNARE-dependent lipid mixing in the absence of a major Ca(2+) sensor synapto...

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Vydáno v:J Biol Chem
Hlavní autoři: Lou, Xiaochu, Shin, Jaeil, Yang, Yoosoo, Kim, Jaewook, Shin, Yeon-Kyun
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400360/
https://ncbi.nlm.nih.gov/pubmed/25716321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631341
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