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Large α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle docking
Parkinson disease and dementia with Lewy bodies are featured with the formation of Lewy bodies composed mostly of α-synuclein (α-Syn) in the brain. Although evidence indicates that the large oligomeric or protofibril forms of α-Syn are neurotoxic agents, the detailed mechanisms of the toxic function...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3593925/ https://ncbi.nlm.nih.gov/pubmed/23431141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218424110 |
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