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Cooperative inhibition of SNARE-mediated vesicle fusion by α-synuclein monomers and oligomers

The primary hallmark of Parkinson's disease (PD) is the generation of Lewy bodies of which major component is α-synuclein (α-Syn). Because of increasing evidence of the fundamental roles of α-Syn oligomers in disease progression, α-Syn oligomers have become potential targets for therapeutic int...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Yoo, Gyeongji, Yeou, Sanghun, Son, Jung Bae, Shin, Yeon-Kyun, Lee, Nam Ki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155056/
https://ncbi.nlm.nih.gov/pubmed/34040104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90503-0
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