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Internalization of α-synuclein oligomers into SH-SY5Y cells

Aggregates of misfolded α-synuclein are a distinctive feature of Parkinson’s disease. Small oligomers of α-synuclein are thought to be an important neurotoxic agent, and α-synuclein aggregates exhibit prion-like behavior, propagating misfolding between cells. α-Synuclein is internalized by both pass...

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Bibliographic Details
Published in:Biophys J
Main Authors: Shearer, Lindsay J., Petersen, Nils O., Woodside, Michael T.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008326/
https://ncbi.nlm.nih.gov/pubmed/33515601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.12.031
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