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Structural characteristics and membrane interactions of tandem α-synuclein oligomers

Pre-fibrillar oligomers of α-synuclein are thought to be pathogenic molecules leading to neurotoxicity associated with Parkinson’s disease and other neurodegenerative disorders. However, small oligomers are difficult to isolate for study. To gain better insight into the properties of small α-synucle...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Dong, Chunhua, Hoffmann, Marion, Li, Xi, Wang, Meijing, Garen, Craig R., Petersen, Nils O., Woodside, Michael T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928076/
https://ncbi.nlm.nih.gov/pubmed/29712958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25133-0
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