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Structural characteristics and membrane interactions of tandem α-synuclein oligomers

Pre-fibrillar oligomers of α-synuclein are thought to be pathogenic molecules leading to neurotoxicity associated with Parkinson’s disease and other neurodegenerative disorders. However, small oligomers are difficult to isolate for study. To gain better insight into the properties of small α-synucle...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Dong, Chunhua, Hoffmann, Marion, Li, Xi, Wang, Meijing, Garen, Craig R., Petersen, Nils O., Woodside, Michael T.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928076/
https://ncbi.nlm.nih.gov/pubmed/29712958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25133-0
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