Structural characteristics and membrane interactions of tandem α-synuclein oligomers

Pre-fibrillar oligomers of α-synuclein are thought to be pathogenic molecules leading to neurotoxicity associated with Parkinson’s disease and other neurodegenerative disorders. However, small oligomers are difficult to isolate for study. To gain better insight into the properties of small α-synucle...

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Udgivet i:Sci Rep
Main Authors: Dong, Chunhua, Hoffmann, Marion, Li, Xi, Wang, Meijing, Garen, Craig R., Petersen, Nils O., Woodside, Michael T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928076/
https://ncbi.nlm.nih.gov/pubmed/29712958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25133-0
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