GABA(A) receptor signalling mechanisms revealed by structural pharmacology

Type-A γ-aminobutyric receptors (GABA(A)Rs) are ligand-gated chloride channels with a very rich pharmacology. Some of their modulators, including benzodiazepines and general anaesthetics, are among the most successful drugs in clinical use and common substances of abuse. Without reliable structural...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Martin, Itziar Serna, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370056/
https://ncbi.nlm.nih.gov/pubmed/30602790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0832-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados