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Structural basis for GABA(A) receptor potentiation by neurosteroids
Type-A γ-aminobutyric acid receptors (GABA(A)Rs) are the principal mediators of inhibitory neurotransmission in the human brain. Endogenous neurosteroids interact with GABA(A)Rs to regulate acute and chronic anxiety and are potent sedative, analgesic, anticonvulsant and anaesthetic agents. Their mod...
में बचाया:
| में प्रकाशित: | Nat Struct Mol Biol |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166781/ https://ncbi.nlm.nih.gov/pubmed/28991263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3484 |
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